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Jarrod Bailey

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Jarrod Bailey, PhD, FOCAE
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EDITORIAL NOTE: Contents on this page have not yet been confirmed for accuracy by the scientist.

  • Director of Medical Research at the Physicians Committee for Responsible Medicine (PCRM)
  • PhD in genetics and virology from Newcastle University
  • Author of 70+ peer-reviewed papers on human-specific biomedical research
  • Led the Mandatory Alternatives Petition to the FDA
  • Co-founder of Project R&R for chimpanzee release from U.S. laboratories
  • Advocate for replacing animal models with human-relevant methods
Jarrod Bailey
Jarrod Bailey
Credit: oxfordanimalethics.com

Introduction
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Jarrod Bailey, PhD, FOCAE, is a leading researcher and advocate for human-specific biomedical research and the replacement of animal models with more predictive, ethical methods. As Director of Medical Research at PCRM, he drives initiatives to modernize medical research, focusing on human biology and innovative, non-animal methodologies. His work spans publications, policy advocacy, and public engagement to promote responsible and effective science.

Professional Background and Achievements
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Jarrod Bailey earned his BSc with honors in genetics and his PhD in genetics and virology from Newcastle University, England. His early research focused on human premature birth using human tissues and tissue culture methods.

Bailey serves as Director of Medical Research at PCRM, where he leads a team of scientists and develops strategies to shift biomedical research toward human-specific methods. He has presented research and policy recommendations to the U.S. Food and Drug Administration (FDA), Environmental Protection Agency (EPA), Institute of Medicine, and members of the U.S. Congress. His efforts aim to encourage the adoption of validated non-animal methods in research and testing, and to influence funding bodies, publishers, and institutions to critically evaluate animal research.

Bailey is a Fellow of the Oxford Centre for Animal Ethics (FOCAE) and has received recognition for his contributions, including the HUMAIN Award for significant achievements in advancing human-specific biomedical research.

Research Areas and Projects
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Jarrod Bailey’s research focuses on developing experimental systems that accurately replicate human physiology, emphasizing the limitations of animal models due to genetic and physiological differences. His work advocates for human-relevant methods to improve the predictivity, safety, and cost-effectiveness of biomedical research.

Bailey led the Mandatory Alternatives Petition (MAP) to the FDA, which seeks to require the use of validated non-animal methods in biomedical research and testing. He also co-founded Project R&R - Release and Restitution for Chimpanzees in U.S. Laboratories, advocating for an end to invasive chimpanzee research in the United States. His research includes evaluations of the scientific validity and ethical implications of using chimpanzees and other animals in biomedical research, particularly in areas like AIDS vaccine development.

Bailey collaborates with institutions such as University Hospital Southampton NHS FT and the University of Oxford on clinical trials, including the development of a new whooping cough vaccine. He is also involved in the Translational Research Collaboration (TRC), which focuses on early-stage clinical research into infection and antimicrobial resistance (AMR).

Major Publications
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Title Journal Year Link
Developing a global education hub for animal-free innovation ALTEX 2025 link
Breaking down the barriers to animal-free research Replacing Animal Research 2025 link
Institutional animal care and use committees and the challenges of evaluating animal research proposals Res Integr Peer Rev 2025 link
Creating Training Opportunities in New Approach Methodologies for Early-Career Researchers NAM journal 2025 link
Perspective - How complex in vitro models are addressing the challenges of predicting drug-induced liver injury Front. Drug Discov. 2025 link
An analysis of trends in the use of animal and non-animal methods in biomedical research and toxicology publications Front. Lab. Chip. Technol. 2024 link
Ethics and Controversies in Animal Subjects Research and Impact on Clinical Decision-Making Anesthesiology Clinics 2024 link
It’s Time to Review the Three Rs, to Make them More Fit for Purpose in the 21st Century ALTEX 2024 link
Poor Translatability of Biomedical Research Using Animals - A Narrative Review ALTEX 2023 link
Arguments Against Using Nonhuman Primates in Research Springer 2023 link
CRISPR-Mediated Gene Editing: Scientific and Ethical Issues Trends in Biotechnology 2019 link
An assessment of the role of chimpanzees in AIDS vaccine research Alternatives to Laboratory Animals 2008 link

Awards and Recognitions
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Fellow of the Oxford Centre for Animal Ethics (FOCAE) - Awarded for contributions to animal ethics and welfare in research

Media and Public Engagement
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Jarrod Bailey has been featured in numerous radio, television, and print interviews internationally, discussing the limitations of animal models and the benefits of human-specific research methods. He has presented at conferences, workshops, and seminars, and engaged with policymakers, regulators, and the public to promote responsible and effective biomedical research.

In this Physicians Committee webinar (July 1, 2026), Dr. Jarrod Bailey addresses whether experiments using nonhuman primates are necessary, how monkeys are treated in labs, and what alternatives are emerging. He debunks myths about primate experimentation, highlights the scientific limitations of nonhuman primate models, and explains why researchers are shifting toward human-based methods like organoids and tissue chips. The discussion emphasizes that over 100,000 monkeys are used in U.S. labs annually and argues that human-based approaches can improve research outcomes while reducing animal suffering.

Dr. Jarrod Bailey, PhD, presents at the WIST Congress in Cologne, Germany (2018), arguing against the scientific necessity of using non-human primates in neuroscience research. He highlights ethical concerns, the lack of translational success from primate models to human medicine, and advocates for modern, human-based alternatives like organ chips and human cell cultures. The talk is organized by Doctors Against Animal Experiments (Ärzte gegen Tierversuche).

Dr. Jarrod Bailey, Director of Science and Technology at the Center for Contemporary Sciences, discusses the effectiveness and ethics of testing vaccines and medicines on animals (monkeys, ferrets, mice, and dogs). He challenges the scientific necessity of animal testing, citing poor translational results, misleading headlines, and the availability of superior, human-based alternatives. The interview explores why animal models persist despite their limitations and what modern, ethical methods could replace them.

Research Profiles
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ResearchGate
PCRM
PubMed

References
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[1] Breaking down the barriers to animal-free research
[2] Developing a global education hub for animal-free innovation
[3] Perspective - How complex in vitro models are addressing the challenges of predicting drug-induced liver injury
[4] Creating Training Opportunities in New Approach Methodologies for Early-Career Researchers
[5] Poor Translatability of Biomedical Research Using Animals - A Narrative Review
[6] PCRM - Jarrod Bailey Profile
[7] ResearchGate - Jarrod Bailey
[8] PubMed - Jarrod Bailey